Virus Attacks Dormant Bacteria, Offering New Hope in Antibiotic Resistance Fight

Virus Attacks Dormant Bacteria, Offering New Hope in Antibiotic Resistance Fight

After six years of research, teams from the University of Basel and ETH Zurich have discovered a potentially crucial weapon against antibiotic-resistant bacteria: a virus named Paride that preys on and kills dormant bacteria. This bacterium, Pseudomonas aeruginosa, which can cause severe respiratory diseases and potentially fatal pneumonia, often enters a dormant state as a defense mechanism, making it resistant to many forms of treatment. Paride, found on decaying plant matter in a Swiss cemetery, has shown remarkable efficacy in lab tests and mouse experiments when combined with the antibiotic meropenem, killing off 99% of the targeted bacteria. This significant advancement suggests a new method to tackle drug-resistant infections, though researchers emphasize that this is just the beginning of understanding and utilizing phages against superbugs.

Article DOI.