Category: Latest News

Overview of the faecal samples used for the bulk metagenomic sequencing (for bacteriome and phageome) and the metagenomic sequencing of the viral-like particles (VLP) A double-blind, randomised, placebo-controlled clinical trial was conducted by a team in The Netherlands in order to assess the efficacy and safety of sterile faecal filtrate transplantation in individuals with metabolic…

The pathogens that cause urinary tract infections are becoming increasingly resistant to antibiotics. ETH Zurich researchers have now developed a rapid test and a new therapeutic approach using bacteria-​infecting viruses known as phages. In brief ETH Zurich researchers have developed a new rapid test that uses bacteriophages – viruses that infect bacteria – to quickly…

Phages offer a possible solution to bacterial infections that become resistant to antimicrobial agents. Credit: Stocktrek Images, Inc./Alamy Stock Photo Biotech companies are racing to test bacteriophages — some as found in nature, others armed with CRISPR–Cas — to destroy drug-resistant bacteria selectively while keeping the microbiome intact. Bacteriophages are attracting investor support to do the…

Typhoid-conjugate vaccines (TCVs) provide an opportunity to reduce the burden of typhoid fever, caused by Salmonella Typhi, in endemic areas. As policymakers design vaccination strategies, accurate and high-resolution data on disease burden is crucial. However, traditional blood culture-based surveillance is resource-extensive, prohibiting its large-scale and sustainable implementation.  Salmonella Typhi is a water-borne pathogen, and here, Hooda et al.…

“Phage” by Professor Graham Beards is licensed under CC BY-SA 3.0. Nontuberculous Mycobacterium infections, particularly Mycobacterium abscessus, are increasingly common among patients with cystic fibrosis and chronic bronchiectatic lung diseases. Treatment is challenging due to intrinsic antibiotic resistance. Bacteriophage therapy represents a potentially novel approach. Relatively few active lytic phages are available and there is great variation in phage susceptibilities among M.…